BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidat...

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Auteurs principaux:	Kyren A. Lazarus, Fazal Hadi, Elisabetta Zambon, Karsten Bach, Maria-Francesca Santolla, Julie K. Watson, Lucia L. Correia, Madhumita Das, Rosemary Ugur, Sara Pensa, Lukas Becker, Lia S. Campos, Graham Ladds, Pentao Liu, Gerard I. Evan, Frank M. McCaughan, John Le Quesne, Joo-Hyeon Lee, Dinis Calado, Walid T. Khaled
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f44
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spelling	oai:doaj.org-article:fe3fa86c37864591b2b0b229a1e43f442021-12-02T15:33:54ZBCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma10.1038/s41467-018-05790-52041-1723https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f442018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05790-5https://doaj.org/toc/2041-1723Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidate for this devastating disease.Kyren A. LazarusFazal HadiElisabetta ZambonKarsten BachMaria-Francesca SantollaJulie K. WatsonLucia L. CorreiaMadhumita DasRosemary UgurSara PensaLukas BeckerLia S. CamposGraham LaddsPentao LiuGerard I. EvanFrank M. McCaughanJohn Le QuesneJoo-Hyeon LeeDinis CaladoWalid T. KhaledNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyren A. Lazarus Fazal Hadi Elisabetta Zambon Karsten Bach Maria-Francesca Santolla Julie K. Watson Lucia L. Correia Madhumita Das Rosemary Ugur Sara Pensa Lukas Becker Lia S. Campos Graham Ladds Pentao Liu Gerard I. Evan Frank M. McCaughan John Le Quesne Joo-Hyeon Lee Dinis Calado Walid T. Khaled BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
description	Amongst the non-small cell lung cancers, to date, lung squamous cell carcinoma remains the most challenging to treat. Here the authors report BCL11A as an important factor which together with SOX2 can drive lung squamous cell carcinoma development and highlight a potential novel therapeutic candidate for this devastating disease.
format	article
author	Kyren A. Lazarus Fazal Hadi Elisabetta Zambon Karsten Bach Maria-Francesca Santolla Julie K. Watson Lucia L. Correia Madhumita Das Rosemary Ugur Sara Pensa Lukas Becker Lia S. Campos Graham Ladds Pentao Liu Gerard I. Evan Frank M. McCaughan John Le Quesne Joo-Hyeon Lee Dinis Calado Walid T. Khaled
author_facet	Kyren A. Lazarus Fazal Hadi Elisabetta Zambon Karsten Bach Maria-Francesca Santolla Julie K. Watson Lucia L. Correia Madhumita Das Rosemary Ugur Sara Pensa Lukas Becker Lia S. Campos Graham Ladds Pentao Liu Gerard I. Evan Frank M. McCaughan John Le Quesne Joo-Hyeon Lee Dinis Calado Walid T. Khaled
author_sort	Kyren A. Lazarus
title	BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
title_short	BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
title_full	BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
title_fullStr	BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
title_full_unstemmed	BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
title_sort	bcl11a interacts with sox2 to control the expression of epigenetic regulators in lung squamous carcinoma
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/fe3fa86c37864591b2b0b229a1e43f44
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BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

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