COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

Summary: Liver-resident macrophages Kupffer cells (KCs) and infiltrating Ly6Chi monocytes both contribute to liver tissue regeneration in various pathologies but also to disease progression upon disruption of orderly consecutive regeneration cascades. Little is known about molecular pathways that re...

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Autores principales: Keren Cohen, Odelia Mouhadeb, Shani Ben Shlomo, Marva Langer, Anat Neumann, Noam Erez, Itay Moshkovits, Rotem Pelet, Daniel J. Kedar, Eli Brazowski, Martin Guilliams, Helen S. Goodridge, Nathan Gluck, Chen Varol
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/fe477e9d24474de1a974c2e01f7c0b01
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