Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

Methods enabling the synthesis of diverse collections of nature-inspired compounds with potential medicinal use are sought after in drug design. Here, the authors report a build/couple/pair strategy to efficiently construct chiral polycyclic scaffolds and show their diversification for drug discover...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vunnam Srinivasulu, Paul Schilf, Saleh Ibrahim, Monther A. Khanfar, Scott McN Sieburth, Hany Omar, Anusha Sebastian, Raed A. AlQawasmeh, Matthew John O’Connor, Taleb H. Al-Tel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/fe4e0908a13b4e04b9750d85006dd424
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!