Stimulators of mineralization limit the invasive phenotype of human osteosarcoma cells by a mechanism involving impaired invadopodia formation.

<h4>Background</h4>Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures specialized in extracellular matrix proteolysis).<h4>Results&...

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Autores principales: Anna Cmoch, Paulina Podszywalow-Bartnicka, Malgorzata Palczewska, Katarzyna Piwocka, Patrick Groves, Slawomir Pikula
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/fe4e83bacb024bcf9ce213cecfe262c1
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