Stimulators of mineralization limit the invasive phenotype of human osteosarcoma cells by a mechanism involving impaired invadopodia formation.
<h4>Background</h4>Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures specialized in extracellular matrix proteolysis).<h4>Results&...
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Main Authors: | Anna Cmoch, Paulina Podszywalow-Bartnicka, Malgorzata Palczewska, Katarzyna Piwocka, Patrick Groves, Slawomir Pikula |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/fe4e83bacb024bcf9ce213cecfe262c1 |
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