VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism

Abstract The voltage-dependent anion channel 1 (VDAC1) is a key player in mitochondrial function. VDAC1 serves as a gatekeeper mediating the fluxes of ions, nucleotides, and other metabolites across the outer mitochondrial membrane, as well as the release of apoptogenic proteins initiating apoptotic...

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Autores principales: Hadar Klapper-Goldstein, Ankit Verma, Sigal Elyagon, Roni Gillis, Michael Murninkas, Srinivas Pittala, Avijit Paul, Varda Shoshan-Barmatz, Yoram Etzion
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fe4f01af963c46d29e0a0168157ce1cc
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