Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.

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Auteurs principaux: Uri Weissbein, Maya Schachter, Dieter Egli, Nissim Benvenisty
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
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Accès en ligne:https://doaj.org/article/feb5eec70f094e338f1faedb6617ab6c
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