Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.

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Autores principales: Uri Weissbein, Maya Schachter, Dieter Egli, Nissim Benvenisty
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/feb5eec70f094e338f1faedb6617ab6c
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spelling oai:doaj.org-article:feb5eec70f094e338f1faedb6617ab6c2021-12-02T14:39:33ZAnalysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq10.1038/ncomms121442041-1723https://doaj.org/article/feb5eec70f094e338f1faedb6617ab6c2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12144https://doaj.org/toc/2041-1723Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.Uri WeissbeinMaya SchachterDieter EgliNissim BenvenistyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Uri Weissbein
Maya Schachter
Dieter Egli
Nissim Benvenisty
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
description Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.
format article
author Uri Weissbein
Maya Schachter
Dieter Egli
Nissim Benvenisty
author_facet Uri Weissbein
Maya Schachter
Dieter Egli
Nissim Benvenisty
author_sort Uri Weissbein
title Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
title_short Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
title_full Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
title_fullStr Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
title_full_unstemmed Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq
title_sort analysis of chromosomal aberrations and recombination by allelic bias in rna-seq
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/feb5eec70f094e338f1faedb6617ab6c
work_keys_str_mv AT uriweissbein analysisofchromosomalaberrationsandrecombinationbyallelicbiasinrnaseq
AT mayaschachter analysisofchromosomalaberrationsandrecombinationbyallelicbiasinrnaseq
AT dieteregli analysisofchromosomalaberrationsandrecombinationbyallelicbiasinrnaseq
AT nissimbenvenisty analysisofchromosomalaberrationsandrecombinationbyallelicbiasinrnaseq
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