Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis

Abstract Therapeutic hypothermia (HT) is standard care for term infants with hypoxic–ischaemic (HI) encephalopathy. However, the efficacy of HT in preclinical models, such as the Vannucci model of unilateral HI in the newborn rat, is often greater than that reported from clinical trials. Here, we re...

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Autores principales: Thomas R. Wood, Julia K. Gundersen, Mari Falck, Elke Maes, Damjan Osredkar, Else Marit Løberg, Hemmen Sabir, Lars Walløe, Marianne Thoresen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/feb62e6a11344e0da9ff0aee5d584154
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