Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution

Precision design of DNA origami needs precision validation. Here, the authors developed cryo-EM methods for obtaining high resolution structural data and for constructing pseudo-atomic models in a semi-automated fashion, allowing for iterative nanodevice inspection and refinement.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Massimo Kube, Fabian Kohler, Elija Feigl, Baki Nagel-Yüksel, Elena M. Willner, Jonas J. Funke, Thomas Gerling, Pierre Stömmer, Maximilian N. Honemann, Thomas G. Martin, Sjors H. W. Scheres, Hendrik Dietz
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/fef625b2e3904bd18533db01a9a93d13
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!