Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage

Abstract Pertussis has made a spectacular rebound in countries that have switched from whole-cell (wPV) to acellular pertussis vaccines (aPV). Here, we show that, unlike wPV, aPV, while protective against lung colonization by Bordetella pertussis (Bp), did not protect BALB/c mice from nasal coloniza...

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Auteurs principaux: Violaine Dubois, Jonathan Chatagnon, Anaïs Thiriard, Hélène Bauderlique-Le Roy, Anne-Sophie Debrie, Loïc Coutte, Camille Locht
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ff144e7514f74fce98731758573f1a89
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