Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show its oncogenic role in oral carcinogenesis.

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Auteurs principaux: Jing-Wen Shih, Wei-Fan Chiang, Alexander T. H. Wu, Ming-Heng Wu, Ling-Yu Wang, Yen-Ling Yu, Yu-Wen Hung, Wen-Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung, Chun A. Changou, Yun Yen, Hsing-Jien Kung
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Science
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Accès en ligne:https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a
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Internet

https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a

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