Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show its oncogenic role in oral carcinogenesis.

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Autores principales:	Jing-Wen Shih, Wei-Fan Chiang, Alexander T. H. Wu, Ming-Heng Wu, Ling-Yu Wang, Yen-Ling Yu, Yu-Wen Hung, Wen-Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung, Chun A. Changou, Yun Yen, Hsing-Jien Kung
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a
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spelling	oai:doaj.org-article:ff34e185f1024152aa1e6a455b70c21a2021-12-02T15:39:04ZLong noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression10.1038/ncomms158742041-1723https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15874https://doaj.org/toc/2041-1723Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show its oncogenic role in oral carcinogenesis.Jing-Wen ShihWei-Fan ChiangAlexander T. H. WuMing-Heng WuLing-Yu WangYen-Ling YuYu-Wen HungWen-Chang WangCheng-Ying ChuChiu-Lien HungChun A. ChangouYun YenHsing-Jien KungNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jing-Wen Shih Wei-Fan Chiang Alexander T. H. Wu Ming-Heng Wu Ling-Yu Wang Yen-Ling Yu Yu-Wen Hung Wen-Chang Wang Cheng-Ying Chu Chiu-Lien Hung Chun A. Changou Yun Yen Hsing-Jien Kung Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
description	Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show its oncogenic role in oral carcinogenesis.
format	article
author	Jing-Wen Shih Wei-Fan Chiang Alexander T. H. Wu Ming-Heng Wu Ling-Yu Wang Yen-Ling Yu Yu-Wen Hung Wen-Chang Wang Cheng-Ying Chu Chiu-Lien Hung Chun A. Changou Yun Yen Hsing-Jien Kung
author_facet	Jing-Wen Shih Wei-Fan Chiang Alexander T. H. Wu Ming-Heng Wu Ling-Yu Wang Yen-Ling Yu Yu-Wen Hung Wen-Chang Wang Cheng-Ying Chu Chiu-Lien Hung Chun A. Changou Yun Yen Hsing-Jien Kung
author_sort	Jing-Wen Shih
title	Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
title_short	Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
title_full	Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
title_fullStr	Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
title_full_unstemmed	Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
title_sort	long noncoding rna lnchifcar/mir31hg is a hif-1α co-activator driving oral cancer progression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a
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Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

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