Exosomes for gene therapy effectively inhibit the endothelial-mesenchymal transition in mouse aortic endothelial cells

Abstract Background Heterotopic ossification (HO) can limit joint activity, causes ankylosis and impairs the function and rehabilitation of patients. Endothelial to mesenchymal transition (EndMT) plays an important role in the pathogenesis of HO, and high expression of SMAD7(Mothers Against Decapent...

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Auteurs principaux: Zhenyuan Wei, Yang Zhao, Peichun Hsu, Shang Guo, Chi Zhang, Biao Zhong
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/ff8018cd0a0b4418be8ec211d33944c9
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