Inclusion of a degron reduces levelsof undesired inteins after AAV-mediated proteintrans-splicing in the retina
Split intein-mediated protein trans-splicing expands AAV transfer capacity, thus overcoming the limited AAV cargo. However, non-mammalian inteins persist as trans-splicing by-products, and this could raise safety concerns for AAV intein clinical applications. In this study, we tested the ability of...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Elsevier
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/ff90e9e823594252bf35342e1bb5bf45 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|