The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation

Cas5 is a transcriptional regulator of responses to cell wall stress in the fungal pathogen Candida albicans. Here, Xie et al. show that Cas5 also modulates cell cycle dynamics and responses to antifungal drugs.

Guardado en:
Detalles Bibliográficos
Autores principales: Jinglin L. Xie, Longguang Qin, Zhengqiang Miao, Ben T. Grys, Jacinto De La Cruz Diaz, Kenneth Ting, Jonathan R. Krieger, Jiefei Tong, Kaeling Tan, Michelle D. Leach, Troy Ketela, Michael F. Moran, Damian J. Krysan, Charles Boone, Brenda J. Andrews, Anna Selmecki, Koon Ho Wong, Nicole Robbins, Leah E. Cowen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/ffb813afe4d54f829962b3863b93dbc3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ffb813afe4d54f829962b3863b93dbc3
record_format dspace
spelling oai:doaj.org-article:ffb813afe4d54f829962b3863b93dbc32021-12-02T14:40:24ZThe Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation10.1038/s41467-017-00547-y2041-1723https://doaj.org/article/ffb813afe4d54f829962b3863b93dbc32017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00547-yhttps://doaj.org/toc/2041-1723Cas5 is a transcriptional regulator of responses to cell wall stress in the fungal pathogen Candida albicans. Here, Xie et al. show that Cas5 also modulates cell cycle dynamics and responses to antifungal drugs.Jinglin L. XieLongguang QinZhengqiang MiaoBen T. GrysJacinto De La Cruz DiazKenneth TingJonathan R. KriegerJiefei TongKaeling TanMichelle D. LeachTroy KetelaMichael F. MoranDamian J. KrysanCharles BooneBrenda J. AndrewsAnna SelmeckiKoon Ho WongNicole RobbinsLeah E. CowenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jinglin L. Xie
Longguang Qin
Zhengqiang Miao
Ben T. Grys
Jacinto De La Cruz Diaz
Kenneth Ting
Jonathan R. Krieger
Jiefei Tong
Kaeling Tan
Michelle D. Leach
Troy Ketela
Michael F. Moran
Damian J. Krysan
Charles Boone
Brenda J. Andrews
Anna Selmecki
Koon Ho Wong
Nicole Robbins
Leah E. Cowen
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
description Cas5 is a transcriptional regulator of responses to cell wall stress in the fungal pathogen Candida albicans. Here, Xie et al. show that Cas5 also modulates cell cycle dynamics and responses to antifungal drugs.
format article
author Jinglin L. Xie
Longguang Qin
Zhengqiang Miao
Ben T. Grys
Jacinto De La Cruz Diaz
Kenneth Ting
Jonathan R. Krieger
Jiefei Tong
Kaeling Tan
Michelle D. Leach
Troy Ketela
Michael F. Moran
Damian J. Krysan
Charles Boone
Brenda J. Andrews
Anna Selmecki
Koon Ho Wong
Nicole Robbins
Leah E. Cowen
author_facet Jinglin L. Xie
Longguang Qin
Zhengqiang Miao
Ben T. Grys
Jacinto De La Cruz Diaz
Kenneth Ting
Jonathan R. Krieger
Jiefei Tong
Kaeling Tan
Michelle D. Leach
Troy Ketela
Michael F. Moran
Damian J. Krysan
Charles Boone
Brenda J. Andrews
Anna Selmecki
Koon Ho Wong
Nicole Robbins
Leah E. Cowen
author_sort Jinglin L. Xie
title The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
title_short The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
title_full The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
title_fullStr The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
title_full_unstemmed The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
title_sort candida albicans transcription factor cas5 couples stress responses, drug resistance and cell cycle regulation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ffb813afe4d54f829962b3863b93dbc3
work_keys_str_mv AT jinglinlxie thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT longguangqin thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT zhengqiangmiao thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT bentgrys thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jacintodelacruzdiaz thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT kennethting thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jonathanrkrieger thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jiefeitong thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT kaelingtan thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT michelledleach thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT troyketela thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT michaelfmoran thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT damianjkrysan thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT charlesboone thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT brendajandrews thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT annaselmecki thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT koonhowong thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT nicolerobbins thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT leahecowen thecandidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jinglinlxie candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT longguangqin candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT zhengqiangmiao candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT bentgrys candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jacintodelacruzdiaz candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT kennethting candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jonathanrkrieger candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT jiefeitong candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT kaelingtan candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT michelledleach candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT troyketela candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT michaelfmoran candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT damianjkrysan candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT charlesboone candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT brendajandrews candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT annaselmecki candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT koonhowong candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT nicolerobbins candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
AT leahecowen candidaalbicanstranscriptionfactorcas5couplesstressresponsesdrugresistanceandcellcycleregulation
_version_ 1718390335407652864