A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling.

por Ian S Hsu, Bob Strome, Emma Lash, Nicole Robbins, Leah E Cowen, Alan M Moses
Publicado 2021

Staurosporine Induces Filamentation in the Human Fungal Pathogen <named-content content-type="genus-species">Candida albicans</named-content> via Signaling through Cyr1 and Protein...

por Jinglin L. Xie, Teresa R. O’Meara, Elizabeth J. Polvi, Nicole Robbins, Leah E. Cowen
Publicado 2017

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen <named-content content-type="genus-species">Candida auris</name...

por Kali R. Iyer, Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins, Leah E. Cowen
Publicado 2020

Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic <italic toggle="yes">Candida</italic> Species

por Nicole M. Revie, Nicole Robbins, Luke Whitesell, John R. Frost, Solomon D. Appavoo, Andrei K. Yudin, Leah E. Cowen
Publicado 2020

Erratum for Kim et al., “Genetic Analysis of <named-content content-type="genus-species">Candida auris</named-content> Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr...

por Sang Hu Kim, Kali R. Iyer, Lakhansing Pardeshi, José F. Muñoz, Nicole Robbins, Christina A. Cuomo, Koon Ho Wong, Leah E. Cowen
Publicado 2019

Genetic Analysis of <italic toggle="yes">Candida auris</italic> Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance

por Sang Hu Kim, Kali R. Iyer, Lakhansing Pardeshi, José F. Muñoz, Nicole Robbins, Christina A. Cuomo, Koon Ho Wong, Leah E. Cowen
Publicado 2019

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation

por Jinglin L. Xie, Longguang Qin, Zhengqiang Miao, Ben T. Grys, Jacinto De La Cruz Diaz, Kenneth Ting, Jonathan R. Krieger, Jiefei Tong, Kaeling Tan, Michelle D. Leach, Troy Ketela, Michael F. Moran, Damian J. Krysan, Charles Boone, Brenda J. Andrews, Anna Selmecki, Koon Ho Wong, Nicole Robbins, Leah E. Cowen
Publicado 2017

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

por Luke Whitesell, Nicole Robbins, David S. Huang, Catherine A. McLellan, Tanvi Shekhar-Guturja, Emmanuelle V. LeBlanc, Catherine S. Nation, Raymond Hui, Ashley Hutchinson, Cathy Collins, Sharanya Chatterjee, Richard Trilles, Jinglin L. Xie, Damian J. Krysan, Susan Lindquist, John A. Porco, Utpal Tatu, Lauren E. Brown, Juan Pizarro, Leah E. Cowen
Publicado 2019

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

por Kali R. Iyer, Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila M. Pimentel-Elardo, Jen L. Fossen, Karen Marchillo, Zhongle Liu, Shakti Singh, José F. Muñoz, Sang Hu Kim, John A. Porco, Christina A. Cuomo, Noelle S. Williams, Ashraf S. Ibrahim, John E. Edwards, David R. Andes, Justin R. Nodwell, Lauren E. Brown, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Publicado 2020

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

por Ci Fu, Xiang Zhang, Amanda O. Veri, Kali R. Iyer, Emma Lash, Alice Xue, Huijuan Yan, Nicole M. Revie, Cassandra Wong, Zhen-Yuan Lin, Elizabeth J. Polvi, Sean D. Liston, Benjamin VanderSluis, Jing Hou, Yoko Yashiroda, Anne-Claude Gingras, Charles Boone, Teresa R. O’Meara, Matthew J. O’Meara, Suzanne Noble, Nicole Robbins, Chad L. Myers, Leah E. Cowen
Publicado 2021