Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen <named-content content-type="genus-species">Candida auris</name...

par Kali R. Iyer, Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins, Leah E. Cowen
Publié 2020

Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic <italic toggle="yes">Candida</italic> Species

par Nicole M. Revie, Nicole Robbins, Luke Whitesell, John R. Frost, Solomon D. Appavoo, Andrei K. Yudin, Leah E. Cowen
Publié 2020

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

par Luke Whitesell, Nicole Robbins, David S. Huang, Catherine A. McLellan, Tanvi Shekhar-Guturja, Emmanuelle V. LeBlanc, Catherine S. Nation, Raymond Hui, Ashley Hutchinson, Cathy Collins, Sharanya Chatterjee, Richard Trilles, Jinglin L. Xie, Damian J. Krysan, Susan Lindquist, John A. Porco, Utpal Tatu, Lauren E. Brown, Juan Pizarro, Leah E. Cowen
Publié 2019

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

par Kali R. Iyer, Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila M. Pimentel-Elardo, Jen L. Fossen, Karen Marchillo, Zhongle Liu, Shakti Singh, José F. Muñoz, Sang Hu Kim, John A. Porco, Christina A. Cuomo, Noelle S. Williams, Ashraf S. Ibrahim, John E. Edwards, David R. Andes, Justin R. Nodwell, Lauren E. Brown, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Publié 2020