Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis.

Enterohemorrhagic Escherichia coli (EHEC) strains cause diarrhea and hemolytic uremic syndrome resulting from toxin-mediated microvascular endothelial injury. EHEC hemolysin (EHEC-Hly), a member of the RTX (repeats-in-toxin) family, is an EHEC virulence factor of increasingly recognized importance....

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Auteurs principaux: Martina Bielaszewska, Christian Rüter, Lisa Kunsmann, Lilo Greune, Andreas Bauwens, Wenlan Zhang, Thorsten Kuczius, Kwang Sik Kim, Alexander Mellmann, M Alexander Schmidt, Helge Karch
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ffbde44ba8924d3caffa85a8e91511b4
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