BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.

<h4>Background/aims</h4>Brown adipose tissue (BAT) dissipates energy stored in triglycerides as heat via the uncoupling protein UCP-1 and is a promising target to combat hyperlipidemia and obesity. BAT is densely innervated by the sympathetic nervous system, which increases BAT different...

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Main Authors: Mariëtte R Boon, Sjoerd A A van den Berg, Yanan Wang, Jan van den Bossche, Sofia Karkampouna, Matthias Bauwens, Marijke De Saint-Hubert, Geertje van der Horst, Slobodan Vukicevic, Menno P J de Winther, Louis M Havekes, J Wouter Jukema, Jouke T Tamsma, Gabri van der Pluijm, Ko Willems van Dijk, Patrick C N Rensen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/ffe1798349a646ec9e836dd6d43dd936
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https://doaj.org/article/ffe1798349a646ec9e836dd6d43dd936

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