Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines

Large RNAs and ribonucleoprotein complexes have shown potential as novel therapeutic agents, but their targeted delivery to cells is still challenging. Here the authors present a modular aptamer nanostructure for intracellular delivery of RNAs up to 250 nucleotides to cancer cells.

Guardado en:
Detalles Bibliográficos
Autores principales: David Porciani, Leah N. Cardwell, Kwaku D. Tawiah, Khalid K. Alam, Margaret J. Lange, Mark A. Daniels, Donald H. Burke
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/ffee912c372c4f2bb7d08733a0e28329
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!