Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

Abstract Cigarette smoking is an established environmental risk factor for Multiple Sclerosis (MS), a chronic inflammatory and neurodegenerative disease, although a mechanistic basis remains largely unknown. We aimed at investigating how smoking affects blood DNA methylation in MS patients, by assay...

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Main Authors: Francesco Marabita, Malin Almgren, Louise K. Sjöholm, Lara Kular, Yun Liu, Tojo James, Nimrod B. Kiss, Andrew P. Feinberg, Tomas Olsson, Ingrid Kockum, Lars Alfredsson, Tomas J. Ekström, Maja Jagodic
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/fff67ede152e42ca99d2c835f14f77b1
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https://doaj.org/article/fff67ede152e42ca99d2c835f14f77b1

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