Structural basis for the multi-activity factor Rad5 in replication stress tolerance

Structural basis for the multi-activity factor Rad5 in replication stress tolerance

Rad5 is a hub connecting three replication stress tolerance pathways. Here, the authors present the 3.3 Å crystal structure of a N-terminal truncated K.lactis Rad5 construct that reveals the spatial arrangement of the HIRAN, Snf2 and RING domains and structure-guided in vitro and in vivo experiments...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Miaomiao Shen, Nalini Dhingra, Quan Wang, Chen Cheng, Songbiao Zhu, Xiaolin Tian, Jun Yu, Xiaoxin Gong, Xuzhichao Li, Hongwei Zhang, Xin Xu, Liting Zhai, Min Xie, Ying Gao, Haiteng Deng, Yongning He, Hengyao Niu, Xiaolan Zhao, Song Xiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/fffc4fbf2bca4bedb24e1f3731229166
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/fffc4fbf2bca4bedb24e1f3731229166

Ejemplares similares