Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas

Background: Leptin, a product of ob gene and insulin blood levels, are proportional to the amount of adipose tissue. Insulin could have an independent regulatory effect on leptin secretion. Aim: To assess the relationship between serum leptin and plasma insulin levels in obese and lean Chilean women...

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Autores principales:	Albala B,Cecilia, Pérez B,Francisco, Santos M,José Luis, Yáñez G,Mabel, Arroyo A,Patricia, Díaz C,Jaime, Díaz B,Erik
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2000
Materias:	Body mass index Insulin Insulin resistance Leptin Obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200004
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spelling	oai:scielo:S0034-988720000002000042014-05-06Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesasAlbala B,CeciliaPérez B,FranciscoSantos M,José LuisYáñez G,MabelArroyo A,PatriciaDíaz C,JaimeDíaz B,Erik Body mass index Insulin Insulin resistance Leptin Obesity Background: Leptin, a product of ob gene and insulin blood levels, are proportional to the amount of adipose tissue. Insulin could have an independent regulatory effect on leptin secretion. Aim: To assess the relationship between serum leptin and plasma insulin levels in obese and lean Chilean women. Material and methods: One hundred forty five women, aged 20 to 60 years old, were studied. Weight, height, waist and hip circumference, fasting blood glucose, insulin and leptin levels were measured. Insulin resistance was assessed using the homeostasis model assessment. The relationship between different variables was determined using multiple linear regression, variance analysis and non parametric correlation. Results: Leptin serum concentrations were positively correlated with body mass index, insulin plasma levels and degree of insulin resistance. The association of leptin with insulin was independent of body mass index and persisted after adjustments by body fat distribution and age. Conclusions: Insulin and insulin resistance are associated to high blood leptin levels and this association is independent of the degree of adiposity and body fat distribution.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.128 n.2 20002000-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200004es10.4067/S0034-98872000000200004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Body mass index Insulin Insulin resistance Leptin Obesity
spellingShingle	Body mass index Insulin Insulin resistance Leptin Obesity Albala B,Cecilia Pérez B,Francisco Santos M,José Luis Yáñez G,Mabel Arroyo A,Patricia Díaz C,Jaime Díaz B,Erik Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
description	Background: Leptin, a product of ob gene and insulin blood levels, are proportional to the amount of adipose tissue. Insulin could have an independent regulatory effect on leptin secretion. Aim: To assess the relationship between serum leptin and plasma insulin levels in obese and lean Chilean women. Material and methods: One hundred forty five women, aged 20 to 60 years old, were studied. Weight, height, waist and hip circumference, fasting blood glucose, insulin and leptin levels were measured. Insulin resistance was assessed using the homeostasis model assessment. The relationship between different variables was determined using multiple linear regression, variance analysis and non parametric correlation. Results: Leptin serum concentrations were positively correlated with body mass index, insulin plasma levels and degree of insulin resistance. The association of leptin with insulin was independent of body mass index and persisted after adjustments by body fat distribution and age. Conclusions: Insulin and insulin resistance are associated to high blood leptin levels and this association is independent of the degree of adiposity and body fat distribution.
author	Albala B,Cecilia Pérez B,Francisco Santos M,José Luis Yáñez G,Mabel Arroyo A,Patricia Díaz C,Jaime Díaz B,Erik
author_facet	Albala B,Cecilia Pérez B,Francisco Santos M,José Luis Yáñez G,Mabel Arroyo A,Patricia Díaz C,Jaime Díaz B,Erik
author_sort	Albala B,Cecilia
title	Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
title_short	Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
title_full	Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
title_fullStr	Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
title_full_unstemmed	Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
title_sort	relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas
publisher	Sociedad Médica de Santiago
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000200004
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Relación entre leptina e insulina sanguíneas en mujeres chilenas obesas y no obesas

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