Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?

Background: There is a correlation between aging and the decrease of plasma levels of vitamin B-12. Aim: To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM). Material and Methods: Cross-sectional study, in 1028 subjects aged 65 to 87...

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Autores principales:	SÁNCHEZ,HUGO, ALBALA,CECILIA, HERTRAMPF,EVA, VERDUGO,RENATO, LAVADOS,MANUEL, CASTILLO,JOSÉ LUIS, LERA,LYDIA, UAUY,RICARDO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Aged Anemia, macrocytic Vitamin B12
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000100006
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spelling	oai:scielo:S0034-988720100001000062010-05-10Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?SÁNCHEZ,HUGOALBALA,CECILIAHERTRAMPF,EVAVERDUGO,RENATOLAVADOS,MANUELCASTILLO,JOSÉ LUISLERA,LYDIAUAUY,RICARDO Aged Anemia, macrocytic Vitamin B12 Background: There is a correlation between aging and the decrease of plasma levels of vitamin B-12. Aim: To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM). Material and Methods: Cross-sectional study, in 1028 subjects aged 65 to 87years, living in community and evaluated between 2005 and 2008. Percentile distribution of vitamin B-12, folate, hemoglobin, packed red cell volume and mean cell volume by gender and age were analyzed. Deficiency was defined as vitamin B-12 levels < 148 pmol/L, marginal deficiency as vitamin B-12 levels < 221 pmol/L, anemia was defined as a hemoglobin < 13 and 12 g/dL among men and women, respectively. Results: The prevalence of vitamin B-12 deficiency was 12% and the figure for marginal deficiency was 25.4%. Males were more affected than females (p < 0.001). The frequency of anemia was 8.6%o, and was higher among women (p = 0.004). Conclusions: There is a high prevalence of full blown and marginal deficit of vitamin B-12 among the elderly. This deficiency should be considered for correction through public nutrition policies.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.1 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000100006es10.4067/S0034-98872010000100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Aged Anemia, macrocytic Vitamin B12
spellingShingle	Aged Anemia, macrocytic Vitamin B12 SÁNCHEZ,HUGO ALBALA,CECILIA HERTRAMPF,EVA VERDUGO,RENATO LAVADOS,MANUEL CASTILLO,JOSÉ LUIS LERA,LYDIA UAUY,RICARDO Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
description	Background: There is a correlation between aging and the decrease of plasma levels of vitamin B-12. Aim: To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM). Material and Methods: Cross-sectional study, in 1028 subjects aged 65 to 87years, living in community and evaluated between 2005 and 2008. Percentile distribution of vitamin B-12, folate, hemoglobin, packed red cell volume and mean cell volume by gender and age were analyzed. Deficiency was defined as vitamin B-12 levels < 148 pmol/L, marginal deficiency as vitamin B-12 levels < 221 pmol/L, anemia was defined as a hemoglobin < 13 and 12 g/dL among men and women, respectively. Results: The prevalence of vitamin B-12 deficiency was 12% and the figure for marginal deficiency was 25.4%. Males were more affected than females (p < 0.001). The frequency of anemia was 8.6%o, and was higher among women (p = 0.004). Conclusions: There is a high prevalence of full blown and marginal deficit of vitamin B-12 among the elderly. This deficiency should be considered for correction through public nutrition policies.
author	SÁNCHEZ,HUGO ALBALA,CECILIA HERTRAMPF,EVA VERDUGO,RENATO LAVADOS,MANUEL CASTILLO,JOSÉ LUIS LERA,LYDIA UAUY,RICARDO
author_facet	SÁNCHEZ,HUGO ALBALA,CECILIA HERTRAMPF,EVA VERDUGO,RENATO LAVADOS,MANUEL CASTILLO,JOSÉ LUIS LERA,LYDIA UAUY,RICARDO
author_sort	SÁNCHEZ,HUGO
title	Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
title_short	Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
title_full	Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
title_fullStr	Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
title_full_unstemmed	Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?
title_sort	déficit de vitamina b-12 en adultos mayores: ¿un problema de salud pública en chile?
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000100006
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Déficit de vitamina B-12 en adultos mayores: ¿Un problema de salud pública en Chile?

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