Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal

Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb los...

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Autores principales: Zárate B.,Cristian, Martínez R-E.,María Eugenia, Sfeir V.,Pedro, Drazic B.,Obren, Vargas S.,José F, Torrealba F.,José I., Bergoeing R.,Michel, Mariné M.,Leopoldo, Valdés E.,Francisco, Mertens M.,Renato
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001001513
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spelling oai:scielo:S0034-988720200010015132021-02-02Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporalZárate B.,CristianMartínez R-E.,María EugeniaSfeir V.,PedroDrazic B.,ObrenVargas S.,José FTorrealba F.,José I.Bergoeing R.,MichelMariné M.,LeopoldoValdés E.,FranciscoMertens M.,Renato Arteritis Giant Cells Giant Cell Arteritis Femoral Artery Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb loss. We report a 73-year-old woman presenting with a one-month history of lower extremity intermittent claudication of sudden onset. She also complained of fever, malaise, headache and weight loss. A non-invasive vascular study showed moderate femoral popliteal occlusive disease, with and abnormal ankle-brachial index (0.68 and 0.83 on right and left sides, respectively). An angio-computed tomography showed thickening of the aortic wall and severe stenosis in both superficial femoral arteries. Steroidal treatment was started, and a temporal artery biopsy was performed confirming giant cell arteritis. Six weeks after steroid therapy the patient had a complete remission of symptoms. A serologic exacerbation was subsequently treated with a humanized monoclonal antibody against the interleukin-6 receptor Tocilizumab, obtaining long time remission.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.10 20202020-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001001513es10.4067/S0034-98872020001001513
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Arteritis
Giant Cells
Giant Cell Arteritis
Femoral Artery
spellingShingle Arteritis
Giant Cells
Giant Cell Arteritis
Femoral Artery
Zárate B.,Cristian
Martínez R-E.,María Eugenia
Sfeir V.,Pedro
Drazic B.,Obren
Vargas S.,José F
Torrealba F.,José I.
Bergoeing R.,Michel
Mariné M.,Leopoldo
Valdés E.,Francisco
Mertens M.,Renato
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
description Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb loss. We report a 73-year-old woman presenting with a one-month history of lower extremity intermittent claudication of sudden onset. She also complained of fever, malaise, headache and weight loss. A non-invasive vascular study showed moderate femoral popliteal occlusive disease, with and abnormal ankle-brachial index (0.68 and 0.83 on right and left sides, respectively). An angio-computed tomography showed thickening of the aortic wall and severe stenosis in both superficial femoral arteries. Steroidal treatment was started, and a temporal artery biopsy was performed confirming giant cell arteritis. Six weeks after steroid therapy the patient had a complete remission of symptoms. A serologic exacerbation was subsequently treated with a humanized monoclonal antibody against the interleukin-6 receptor Tocilizumab, obtaining long time remission.
author Zárate B.,Cristian
Martínez R-E.,María Eugenia
Sfeir V.,Pedro
Drazic B.,Obren
Vargas S.,José F
Torrealba F.,José I.
Bergoeing R.,Michel
Mariné M.,Leopoldo
Valdés E.,Francisco
Mertens M.,Renato
author_facet Zárate B.,Cristian
Martínez R-E.,María Eugenia
Sfeir V.,Pedro
Drazic B.,Obren
Vargas S.,José F
Torrealba F.,José I.
Bergoeing R.,Michel
Mariné M.,Leopoldo
Valdés E.,Francisco
Mertens M.,Renato
author_sort Zárate B.,Cristian
title Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
title_short Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
title_full Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
title_fullStr Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
title_full_unstemmed Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
title_sort isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001001513
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