Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal
Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb los...
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Sociedad Médica de Santiago
2020
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oai:scielo:S0034-988720200010015132021-02-02Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporalZárate B.,CristianMartínez R-E.,María EugeniaSfeir V.,PedroDrazic B.,ObrenVargas S.,José FTorrealba F.,José I.Bergoeing R.,MichelMariné M.,LeopoldoValdés E.,FranciscoMertens M.,Renato Arteritis Giant Cells Giant Cell Arteritis Femoral Artery Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb loss. We report a 73-year-old woman presenting with a one-month history of lower extremity intermittent claudication of sudden onset. She also complained of fever, malaise, headache and weight loss. A non-invasive vascular study showed moderate femoral popliteal occlusive disease, with and abnormal ankle-brachial index (0.68 and 0.83 on right and left sides, respectively). An angio-computed tomography showed thickening of the aortic wall and severe stenosis in both superficial femoral arteries. Steroidal treatment was started, and a temporal artery biopsy was performed confirming giant cell arteritis. Six weeks after steroid therapy the patient had a complete remission of symptoms. A serologic exacerbation was subsequently treated with a humanized monoclonal antibody against the interleukin-6 receptor Tocilizumab, obtaining long time remission.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.10 20202020-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001001513es10.4067/S0034-98872020001001513 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Arteritis Giant Cells Giant Cell Arteritis Femoral Artery |
spellingShingle |
Arteritis Giant Cells Giant Cell Arteritis Femoral Artery Zárate B.,Cristian Martínez R-E.,María Eugenia Sfeir V.,Pedro Drazic B.,Obren Vargas S.,José F Torrealba F.,José I. Bergoeing R.,Michel Mariné M.,Leopoldo Valdés E.,Francisco Mertens M.,Renato Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
description |
Giant cell arteritis is more common in women older than 60 years, is associated with systemic inflammation symptoms and mainly involves the aortic arch and cranial arteries, specially the temporal artery. Symptomatic lower extremity arterial stenosis or occlusion is uncommon and can lead to limb loss. We report a 73-year-old woman presenting with a one-month history of lower extremity intermittent claudication of sudden onset. She also complained of fever, malaise, headache and weight loss. A non-invasive vascular study showed moderate femoral popliteal occlusive disease, with and abnormal ankle-brachial index (0.68 and 0.83 on right and left sides, respectively). An angio-computed tomography showed thickening of the aortic wall and severe stenosis in both superficial femoral arteries. Steroidal treatment was started, and a temporal artery biopsy was performed confirming giant cell arteritis. Six weeks after steroid therapy the patient had a complete remission of symptoms. A serologic exacerbation was subsequently treated with a humanized monoclonal antibody against the interleukin-6 receptor Tocilizumab, obtaining long time remission. |
author |
Zárate B.,Cristian Martínez R-E.,María Eugenia Sfeir V.,Pedro Drazic B.,Obren Vargas S.,José F Torrealba F.,José I. Bergoeing R.,Michel Mariné M.,Leopoldo Valdés E.,Francisco Mertens M.,Renato |
author_facet |
Zárate B.,Cristian Martínez R-E.,María Eugenia Sfeir V.,Pedro Drazic B.,Obren Vargas S.,José F Torrealba F.,José I. Bergoeing R.,Michel Mariné M.,Leopoldo Valdés E.,Francisco Mertens M.,Renato |
author_sort |
Zárate B.,Cristian |
title |
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
title_short |
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
title_full |
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
title_fullStr |
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
title_full_unstemmed |
Isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
title_sort |
isquemia de extremidades inferiores secundaria a arteritis de la arteria temporal |
publisher |
Sociedad Médica de Santiago |
publishDate |
2020 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001001513 |
work_keys_str_mv |
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