Scavenger Receptors and Atherosclerosis

Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classe...

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Main Author: RIGOTTI,ATTILIO
Language:English
Published: Sociedad de Biología de Chile 2000
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009
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spelling oai:scielo:S0716-976020000002000092010-02-11Scavenger Receptors and AtherosclerosisRIGOTTI,ATTILIO atherosclerosis cholesterol metabolism lipoprotein scavenger receptor selective cholesterol uptake Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesisinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.33 n.2 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009en10.4067/S0716-97602000000200009
institution Scielo Chile
collection Scielo Chile
language English
topic atherosclerosis
cholesterol metabolism
lipoprotein
scavenger receptor
selective cholesterol uptake
spellingShingle atherosclerosis
cholesterol metabolism
lipoprotein
scavenger receptor
selective cholesterol uptake
RIGOTTI,ATTILIO
Scavenger Receptors and Atherosclerosis
description Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesis
author RIGOTTI,ATTILIO
author_facet RIGOTTI,ATTILIO
author_sort RIGOTTI,ATTILIO
title Scavenger Receptors and Atherosclerosis
title_short Scavenger Receptors and Atherosclerosis
title_full Scavenger Receptors and Atherosclerosis
title_fullStr Scavenger Receptors and Atherosclerosis
title_full_unstemmed Scavenger Receptors and Atherosclerosis
title_sort scavenger receptors and atherosclerosis
publisher Sociedad de Biología de Chile
publishDate 2000
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009
work_keys_str_mv AT rigottiattilio scavengerreceptorsandatherosclerosis
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