The cellular mechanisms of body iron homeostasis
Cells tightly regulate iron levels through the activity of iron regulatory proteins (IRPs) that bind to RNA motifs called iron responsive elements (IREs). When cells become iron-depleted, IRPs bind to IREs present in the mRNAs of ferritin and the transferrin receptor, resulting in diminished transla...
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Autores principales: | , , , , |
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Lenguaje: | English |
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Sociedad de Biología de Chile
2000
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200013 |
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