Genetic polymorphism at position -308 in the promoter region of the tumor necrosis factor (TNF): Implications of its allelic distribution on susceptibility or resistance to diseases in the Chilean population
Several single-nucleotide polymorphisms have been identified in the human TNF gene promoter. The polymorphism at position _308 (TNF-308), which involves substituting G for A and designing the TNF2 allele, leads to a higher rate of TNF gene transcription than the wild-type TNF1 allele in in vitro exp...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Langue: | English |
| Publié: |
Sociedad de Biología de Chile
2001
|
| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000300011 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|