T-kininogen inhibits kinin-mediated activation of ERK in endothelial cells

Serum levels of T-kininogen increase dramatically as rats approach the end of their lifespan. Stable expression of the protein in Balb/c 3T3 fibroblasts leads to a dramatic inhibition of cell proliferation, as well as inhibition of the ERK signaling pathway. T-kininogen is a potent inhibitor of cyst...

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Auteurs principaux: LEIVA-SALCEDO,ELIAS, PEREZ,VIVIANA, ACUÑA-CASTILLO,CLAUDIO, WALTER,ROBIN, SIERRA,FELIPE
Langue:English
Publié: Sociedad de Biología de Chile 2002
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Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200020
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