Grape seed extract proanthocyanidins downregulate HIV- 1 entry coreceptors, CCR2b, CCR3 and CCR5 gene expression by normal peripheral blood mononuclear cells

Grape seed extract proanthocyanidins downregulate HIV- 1 entry coreceptors, CCR2b, CCR3 and CCR5 gene expression by normal peripheral blood mononuclear cells

Flavonoids and related polyphenols, in addition to their cardioprotective, anti-tumor, anti-inflammatory, anti-carcinogenic and anti-allergic activities, also possess promising anti-HIV effects. Recent studies documented that the ß-chemokine receptors, CCR2b, CCR3 and CCR5, and the alpha-chemokine r...

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Autores principales: NAIR,MADHAVAN P, KANDASWAMI,CHITHAN, MAHAJAN,SUPRIYA, NAIR,HARIKRISHNA N, CHAWDA,RAM, SHANAHAN,THOMAS, SCHWARTZ,STANLEY A
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2002
Materias:
PBMC, peripheral blood mononuclear cells
RT- PCR - reverse transcriptase polymerase chain reaction
HIV-1 , human immunodeficiency virus-1 GSE,- Grape Seed Extract
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300016
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