Modulation of sarcoplasmic reticulum calcium release by calsequestrin in cardiac myocytes

Modulation of sarcoplasmic reticulum calcium release by calsequestrin in cardiac myocytes

Calsequestrin (CASQ2) is a high capacity Ca-binding protein expressed inside the sarcoplasmic reticulum (SR). Mutations in the cardiac calsequestrin gene (CASQ2) have been linked to arrhythmias and sudden death induced by exercise and emotional stress. We have studied the function of CASQ2 and the c...

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Bibliographic Details
Main Authors: GYÖRKE,SANDOR, GYÖRKE,INNA, TERENTYEV,DMITRY, VIATCHENKO-KARPINSKI,SERGE, WILLIAMS,SIMON C
Language:English
Published: Sociedad de Biología de Chile 2004
Subjects:
Excitation-contraction coupling
calcium-induced calcium release
ryanodine receptor
calsequestrin
arrhythmia
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400014
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