Effect of 0.25 ppm Ozone exposure on pulmonary damage induced by bleomycin

To study the effect of ozone in a chronically damaged lung, we used a bleomycin (BLM) induced pulmonary fibrosis model. Both endotracheal instillation of BLM and O3 exposure both produce lung inflammation and fibrosis. Oxidative stress would be a common mechanism of damage for both BLM and O3. Our a...

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Auteurs principaux: OYARZÚN,MANUEL, DUSSAUBAT,NELSON, GONZÁLEZ,SERGIO
Langue:English
Publié: Sociedad de Biología de Chile 2005
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Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400007
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