Biological evaluation of novel 6-Arylbenzimidazo [1,2-c] quinazoline derivatives as inhibitors of LPS-induced TNF- alpha secretion

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Biological evaluation of novel 6-Arylbenzimidazo [1,2-c] quinazoline derivatives as inhibitors of LPS-induced TNF- alpha secretion

This study describes the effect of novel 6-Arylbenzimidazo [1,2-c] quinazoline derivatives as tumor necrosis factor alpha (TNF-á) production inhibitors. The newly synthesized compounds were tested for their in vitro ability to inhibit the lipolysaccharide (LPS) induced TNF-á secretion in the human p...

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Autores principales:	GALARCE,GLORIA D, FONCEA,ROCÍO E, EDWARDS,ANA M, PESSOA-MAHANA,HERNÁN, PESSOA-MAHANA,CARLOS D, EBENSPERGER,ROBERTO A
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2008
Materias:	anti-inflammatory agents benzimidazoquinazoline derivatives TNF-á inhibitors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100006
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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