Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant

Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant

In the present work, immunogenicity of recombinant in vitro assembled hepatitis C virus core particles, HCcAg.120-VLPs, either alone or in combination with different adjuvants was evaluated in BALB/c mice. HCcAg.120-VLPs induced high titers of anti-HCcAg.120 antibodies and virus-specific cellular im...

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Autores principales: ACOSTA-RIVERO,NELSON, POUTOU,JOANNA, ÁLVAREZ-LAJONCHERE,LIZ, GUERRA,IVIS, AGUILERA,YARAIMA, MUSACCHIO,ALEXIS, RODRÍGUEZ,ARMANDO, AGUILAR,JULIO C, FALCON,VIVIANA, ÁLVAREZ-OBREGON,JULIO C, SORIA,YORDANKA, TORRES,DINORAH, LINARES,MARBELIS, PÉREZ,ÁNGEL, MORALES-GRILLO,JUAN, DUEÑAS -CARRERA,SANTIAGO
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2009
Materias:
challenge
HCV
immunity
adjuvant
capsid
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100005
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