Reversed phase HPLC determination of zidovudine in rat plasma and its pharmacokinetics after a single intranasal dose administration

The development and validation of a simple and accurate method based on HPLC with ultraviolet detection for the quantification of zidovudine in rat plasma and its application to a pharmacokinetic study following a single intranasal dose zidovudine is described. Zidovudine was extracted from the plas...

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Autores principales: MAINARDES,RUBIANA M, PALMIRA D. GREMIÃO,MARIA
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2009
Materias:
AZT
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300010
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