Donepezil reverses buprenorphine-induced central respiratory depression in anesthetized rabbits
Buprenorphine is a mixed opioid receptor agonist-antagonist used in acute and chronic pain management. Although this agent's analgesic effect increases in a dose-dependent manner, buprenorphine-induced respiratory depression shows a marked ceiling effect at higher doses, which is considered to...
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Autores principales: | , , , , , |
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Lenguaje: | English |
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Sociedad de Biología de Chile
2009
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000400008 |
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