SHh activity and localization is regulated by perlecan

Proliferation and cell fate determination in the developing embryo are extrinsically regulated by multiple interactions among diverse secreted factors, such as Sonic Hedgehog (SHh), which act in a concentration-dependent manner. The fact that SHh is secreted as a lipid-modified protein suggests the...

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Auteurs principaux: Palma,Verónica, Carrasco,Héctor, Reinchisi,Gisela, Olivares,Gonzalo, Faunes,Fernando, Larraín,Juan
Langue:English
Publié: Sociedad de Biología de Chile 2011
Sujets:
SHh
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000100008
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