Human dendritic cells sequentially matured with CD4+ T cells as a secondary signal favor CTL and long-term T memory cell responses

Human dendritic cells sequentially matured with CD4+ T cells as a secondary signal favor CTL and long-term T memory cell responses

Dendritic cells (DCs) are professional antigen-presenting cells involved in the control and initiation of immune responses. In vivo, DCs exposed at the periphery to maturation stimuli migrate to lymph nodes, where they receive secondary signals from CD4+ T helper cells. These DCs become able to init...

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Bibliographic Details
Main Authors: Simon,Thomas, Tanguy-Royer,Séverine, Royer,Pierre-Joseph, Boisgerault,Nicolas, Frikeche,Jihane, Fonteneau,Jean-François, Grégoire,Marc
Language:English
Published: Sociedad de Biología de Chile 2012
Subjects:
Cytotoxic T lymphocytes
dendritic cells
T memory cell
sequential maturation
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100005
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