Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals
We analyzed the in vitro effects of the anti-tumoral drugs doxorubicin, cytosine arabinoside and hydroxyurea on the G2-prophase checkpoint in lymphocytes from healthy individuals. At biologically equivalent concentrations, the induced DNA damage activated the corresponding checkpoint. Thus: i) there...
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Autores principales: | , , , |
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Lenguaje: | English |
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Sociedad de Biología de Chile
2012
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Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000200010 |
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