Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

BACKGROUND: Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. This study was aimed to determ...

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Auteurs principaux: Pieme,Constant Anatole, Santosh,Guru Kumar, Tekwu,Emmanuel Mouafo, Askun,Tülin, Aydeniz,Hatice, Ngogang,Jeanne Yonkeu, Bhushan,Shashi, Saxena,Ajit Kumar
Langue:English
Publié: Sociedad de Biología de Chile 2014
Sujets:
Zanthozyllum heitzii
Syringic acid
Apoptosis
HL-60 cells
ROS
Mitochondrial membrane potential
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100048
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