Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

BACKGROUND: Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. This study was aimed to determ...

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Autores principales: Pieme,Constant Anatole, Santosh,Guru Kumar, Tekwu,Emmanuel Mouafo, Askun,Tülin, Aydeniz,Hatice, Ngogang,Jeanne Yonkeu, Bhushan,Shashi, Saxena,Ajit Kumar
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2014
Materias:
Zanthozyllum heitzii
Syringic acid
Apoptosis
HL-60 cells
ROS
Mitochondrial membrane potential
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100048
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100048

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