Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells

Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells

BACKGROUND: Vascular endothelial growth factor (VEGF) is involved in the growth of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role in mitosis involving in cell proliferation. Simultaneous silencing of VEGF and KSP, an attractive and viable approach in cance...

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Autores principales: Doan,Chung Chinh, Le,Long Thanh, Hoang,Son Nghia, Do,Si Minh, Van Le,Dong
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2014
Materias:
Vascular endothelial cell growth factor (VEGF)
Kinesin spindle protein (KSP)
siRNA cocktail
Proliferation
Apoptosis
Hepatocellular carcinoma
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100064
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100064

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