Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice

BACKGROUND: Nitrosative and oxidative stress play a key role in obesity and diabetes-related mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment on state 3 and 4 oxygen consumption, nitric oxide (NO) synthesis, ATPase activity and lipid oxidation in mitochond...

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Main Authors: Soto-Urquieta,María G, López-Briones,Sergio, Pérez-Vázquez,Victoriano, Saavedra-Molina,Alfredo, González-Hernández,Gloria A, Ramírez-Emiliano,Joel
Language:English
Published: Sociedad de Biología de Chile 2014
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Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100068
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