Integrin-β1, not integrin-β5, mediates osteoblastic differentiation and ECM formation promoted by mechanical tensile strain

Integrin-β1, not integrin-β5, mediates osteoblastic differentiation and ECM formation promoted by mechanical tensile strain

BACKGROUND: Mechanical strain plays a great role in growth and differentiation of osteoblast. A previous study indicated that integrin-β (β1, β5) mediated osteoblast proliferation promoted by mechanical tensile strain. However, the involvement of integrin-β in ost...

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Autores principales: Zeng,Qiangcheng, Guo,Yong, Liu,Yongming, Li,Ruixin, Zhang,Xinchang, Liu,Lu, Wang,Yang, Zhang,Xizheng, Zou,Xianqiong
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2015
Materias:
Tensile strain
Osteoblast
Extracellular matrix
Integrin
siRNA
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100025
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100025

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