BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma

BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma

Abstract Background: Bromodomain-containing protein 4 (BRD4) inhibition is a new therapeutic strategy for many malignancies. In this study, we aimed to explore the effect of BRD4 inhibition by JQ1 on in vitro cell growth, migration and invasion of salivary adenoid cystic carcinoma (SACC). Methods:...

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Bibliographic Details
Main Authors: Wang,Limei, Wu,Xiuyin, Wang,Ruolin, Yang,Chengzhe, Li,Zhi, Wang,Cunwei, Zhang,Fenghe, Yang,Pishan
Language:English
Published: Sociedad de Biología de Chile 2017
Subjects:
Salivary adenoid cystic carcinoma
BRD4 inhibition
Proliferation
Migration
Epithelial-mesenchymal transition
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100213
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100213

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