Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy

Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy

Abstract Background CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. Methods The rats were pretr...

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Autores principales: Zhang,Li, Tan,Jinyun, Jiang,Xiaoping, Qian,Weiwei, Yang,Ting, Sun,Xijun, Chen,Zhaohui, Zhu,Qiwen
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
Materias:
Hepatic encephalopathy
Neuron
Microglia
Chemokine CC motif ligand 2
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100218
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100218

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