Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations

Abstract Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considered high-penetrance BC genes. In non-carriers of BRCA1/2 mutations, disease susce...

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Autores principales: Jara,Lilian, Morales,Sebastian, Mayo,Tomas de, Gonzalez–Hormazabal,Patricio, Carrasco,Valentina, Godoy,Raul
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2017
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100505
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