Protective roles of autophagy in retinal pigment epithelium under high glucose condition via regulating PINK1/Parkin pathway and BNIP3L

Protective roles of autophagy in retinal pigment epithelium under high glucose condition via regulating PINK1/Parkin pathway and BNIP3L

Abstract Background Our study aimed to investigate the roles of autophagy against high glucose induced response in retinal pigment epithelium (ARPE-19 cells). Methods The morphological changes and reactive oxygen species (ROS) generation in ARPE-19 cells under high glucose treatment were respect...

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Main Authors: Huang,Chengchi, Lu,Hong, Xu,Junyu, Yu,Hongmin, Wang,Xiaodan, Zhang,Xiaomei
Language:English
Published: Sociedad de Biología de Chile 2018
Subjects:
Diabetic retinopathy
Retinal pigment epithelium
Autophagy
High glucose
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100219
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602018000100219

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