ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Abstract Background: Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcomes. 4-Amino-2-trifluoromethyl-ph...

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Détails bibliographiques
Auteurs principaux: Feng,Yubin, Hua,Xiaoxiao, Niu,Ruowen, Du,Yan, Shi,Congjian, Zhou,Renpeng, Chen,Fei-Hu
Langue:English
Publié: Sociedad de Biología de Chile 2019
Sujets:
ROS
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100224
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