ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

Abstract Background: Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcomes. 4-Amino-2-trifluoromethyl-ph...

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Autores principales: Feng,Yubin, Hua,Xiaoxiao, Niu,Ruowen, Du,Yan, Shi,Congjian, Zhou,Renpeng, Chen,Fei-Hu
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2019
Materias:
Acute myeloid leukemia
Differentiation
Proliferation
ATPR
ROS
PTEN/PI3K/AKT
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602019000100224
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